Identification of programmed cell death and mitochondria correlated biomarkers for Kawasaki disease by integrated bioinformatics and machine-learning algorithms with RT-qPCR verification

This study defines a novel five-biomarker panel that functionally links mitochondrial dysfunction, dysregulated programmed cell death, and immune activation in Kawasaki disease, providing an integrated, mechanism-based framework for improving diagnosis and guiding future targeted therapies.