Construction and validation of a nomogram based on clinical indicators for 28-day composite poor prognosis prediction in severe sepsis
The constructed nomogram, incorporating intestinal barrier biomarkers and systemic clinical indicators, can help assess intestinal barrier-related risk and provide a reference for predicting adverse outcomes in severe sepsis. It offers a valuable decision-support tool for early goal-directed intervention and demonstrates significant clinical translational potential.
Authors
- Xia Liu (ORCID: https://orcid.org/0000-0002-9209-0562)
- Zhuo Chen (ORCID: https://orcid.org/0000-0002-2166-8005)
- Ruihua Shi (ORCID: https://orcid.org/0000-0002-5604-2731)
- Peng Guo (ORCID: https://orcid.org/0000-0001-7858-4884)
- Xinfu Chen
Institutions
- Xuzhou Medical College (CN)
- Zhongda Hospital Southeast University (CN)
- Affiliated Hospital of Xuzhou Medical College (CN)
Publication Details
- Journal
- Frontiers in Public Health
- Published
- 2026-02-10
- DOI
- https://doi.org/10.3389/fpubh.2026.1709504
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00