Prevalence and diagnostic accuracy of syphilis screening in blood donors: A prospective observational study comparing three different serological platforms

ECLIA proved to be a reliable primary screening tool for syphilis because of its high sensitivity and strong correlation with VDRL titres. RDT showed superior diagnostic accuracy compared to VDRL, supporting its use as a supplementary method in resource-limited settings. These findings highlight the need for robust screening strategies to enhance transfusion safety.