Comparison of Diagnostic Performance Between CT and MRI for Detection of Cartilage Invasion and Tumor Staging in Patients with Laryngeal Cancer: A Systematic Review and Meta-Analysis

MRI had superior diagnostic performance compared to CT in detecting laryngeal cartilage and deep space invasion; it had significantly higher sensitivity, comparable specificity, and lower risk of understaging, thus supporting the use of MRI for accurate pretreatment T-staging. However, given the limited number of studies, the results should be interpreted with caution, and further studies are needed to confirm our findings.

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Publication Details

Journal
Cancers
Published
2026-02-10
DOI
https://doi.org/10.3390/cancers18040583
Primary Topic
Head and Neck Cancer Studies
Type
article
Field-Weighted Citation Impact
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article

Comparison of Diagnostic Performance Between CT and MRI for Detection of Cartilage Invasion and Tumor Staging in Patients with Laryngeal Cancer: A Systematic Review and Meta-Analysis

Emanuela Stan, Dana Emilia Man, B. Dragoș, Razvan Diaconescu et al.
Cancers
Head and Neck Cancer Studies
article

Comparison of Diagnostic Performance Between CT and MRI for Detection of Cartilage Invasion and Tumor Staging in Patients with Laryngeal Cancer: A Systematic Review and Meta-Analysis

Emanuela Stan, Dana Emilia Man, B. Dragoș, Razvan Diaconescu, Andreea-Mihaela Banța, Ingrid-Denisa Barcan, Dan Ionel Orbulescu, Delia Ioana Horhat, Alexandru Catalin Motofelea
article en

Abstract

MRI had superior diagnostic performance compared to CT in detecting laryngeal cartilage and deep space invasion; it had significantly higher sensitivity, comparable specificity, and lower risk of understaging, thus supporting the use of MRI for accurate pretreatment T-staging. However, given the limited number of studies, the results should be interpreted with caution, and further studies are needed to confirm our findings.

CancersVol. 18(4)
Victor Babeș University of Medicine and Pharmacy Timișoara (RO)
Good health and well-being
Openalex Percentile: Top 61%
Head and Neck Cancer Studies
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