Effects of nicotinamide riboside supplementation during late gestation and lactation on sow performance, milk metabolome, and gut microbiome
Maternal supplementation of NR during late gestation and lactation increases sow performance and promotes gut NAD<sup>+</sup> metabolic-associated microbiome remodeling. These findings propose maternal NR intervention as a novel strategy to enhance mammary lactogenesis and lactation metabolism in swine production, with potential applications for therapeutic strategies for lactation insufficiency.
Authors
- Hui Li (ORCID: https://orcid.org/0000-0001-9198-3951)
- De Wu (ORCID: https://orcid.org/0000-0003-1873-9914)
- W. Zhang
- Chenglin Pan
- Long Shuang Huang (ORCID: https://orcid.org/0009-0007-3716-6118)
- Lianqiang Che
- Zhengfeng Fang
- Xiaohan Yang
- Ruilan Zhang
- Shengyu Xu
- Bin Feng
- Yingjie Li
- Ying Li
- Yan Lin
Institutions
- Foshan University (CN)
- Sichuan Agricultural University (CN)
Publication Details
- Journal
- Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
- Published
- 2026-02-10
- DOI
- https://doi.org/10.1186/s40104-025-01339-x
- Primary Topic
- PARP inhibition in cancer therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Sichuan Agricultural University
- Earmarked Fund for China Agriculture Research System