WiraChain: a blockchain and FHIR-based platform for improving clinical data interoperability in healthcare

Interoperability challenges in healthcare frequently lead to fragmented patient records and duplicated procedures, negatively affecting continuity of care and operational efficiency. Although multiple theoretical frameworks and standards have been proposed to address these issues, practical and fully implemented solutions enabling secure and controlled data exchange remain limited. To address this gap, we developed Wirachain, a decentralized application that integrates blockchain technology with the HL7 FHIR standard for electronic health record management. The system enables patient-controlled permission granting and revocation, incorporates authentication and role-based access control, and supports persistent storage using both FHIR-compliant and traditional databases. Validation was conducted using synthetically generated clinical data and stress-testing scenarios to assess system performance under load. The results demonstrate that the proposed application can reliably manage access permissions and clinical data exchange across interoperable components. The system maintained efficient operation and secure data handling under simulated clinical workflows and increased load conditions. These findings indicate that fully implemented blockchain-based solutions can effectively bridge the gap between conceptual interoperability frameworks and practical healthcare applications. Wirachain illustrates the feasibility of combining blockchain and FHIR standards to support secure, patient-centered, and interoperable clinical operations.

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Publication Details

Journal
Frontiers in Public Health
Published
2026-02-10
DOI
https://doi.org/10.3389/fpubh.2026.1746772
Primary Topic
Electronic Health Records Systems
Type
article
Field-Weighted Citation Impact
0.00
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article

WiraChain: a blockchain and FHIR-based platform for improving clinical data interoperability in healthcare

José Santisteban, Leonardo Grau, Joao Urrunaga
Frontiers in Public Health
Electronic Health Records Systems
article

WiraChain: a blockchain and FHIR-based platform for improving clinical data interoperability in healthcare

José Santisteban, Leonardo Grau, Joao Urrunaga
article en

Abstract

Interoperability challenges in healthcare frequently lead to fragmented patient records and duplicated procedures, negatively affecting continuity of care and operational efficiency. Although multiple theoretical frameworks and standards have been proposed to address these issues, practical and fully implemented solutions enabling secure and controlled data exchange remain limited. To address this gap, we developed Wirachain, a decentralized application that integrates blockchain technology with the HL7 FHIR standard for electronic health record management. The system enables patient-controlled permission granting and revocation, incorporates authentication and role-based access control, and supports persistent storage using both FHIR-compliant and traditional databases. Validation was conducted using synthetically generated clinical data and stress-testing scenarios to assess system performance under load. The results demonstrate that the proposed application can reliably manage access permissions and clinical data exchange across interoperable components. The system maintained efficient operation and secure data handling under simulated clinical workflows and increased load conditions. These findings indicate that fully implemented blockchain-based solutions can effectively bridge the gap between conceptual interoperability frameworks and practical healthcare applications. Wirachain illustrates the feasibility of combining blockchain and FHIR standards to support secure, patient-centered, and interoperable clinical operations.

Frontiers in Public HealthVol. 14
Peruvian University of Applied Sciences (PE)
Openalex Percentile: Top 62%
Electronic Health Records Systems
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WiraChain: a blockchain and FHIR-based platform for improving clinical data interoperability in healthcare — José Santisteban, Leonardo Grau, et al. · Frontiers in Public Health (2026) | TGRS Research Map | TGRS