Estimating the prevalence of germline mutations in DNA mismatch repair genes among patients with upper tract urothelial carcinoma: a systematic review and meta-analysis

LS prevalence among patients with UTUC is similar to that among patients with colorectal and endometrial cancers, which provides a strong rationale for LS testing in this population. Further research is necessary to determine the optimal diagnostic strategy.

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Publication Details

Journal
Urologic Oncology Seminars and Original Investigations
Published
2026-02-10
DOI
https://doi.org/10.1016/j.urolonc.2026.110999
Primary Topic
Genetic factors in colorectal cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Estimating the prevalence of germline mutations in DNA mismatch repair genes among patients with upper tract urothelial carcinoma: a systematic review and meta-analysis

Joseph Moryousef, Piotr Zareba, Braden Millan
Urologic Oncology Seminars and Original Investigations
Genetic factors in colorectal cancer
article

Estimating the prevalence of germline mutations in DNA mismatch repair genes among patients with upper tract urothelial carcinoma: a systematic review and meta-analysis

Joseph Moryousef, Piotr Zareba, Braden Millan
article en

Abstract

LS prevalence among patients with UTUC is similar to that among patients with colorectal and endometrial cancers, which provides a strong rationale for LS testing in this population. Further research is necessary to determine the optimal diagnostic strategy.

Urologic Oncology Seminars and Original InvestigationsVol. 44(4)
National Cancer Institute (US), Hamilton Health Sciences (CA), McMaster University (CA)
Good health and well-being
Openalex Percentile: Top 62%
Genetic factors in colorectal cancer
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