Estimating the prevalence of germline mutations in DNA mismatch repair genes among patients with upper tract urothelial carcinoma: a systematic review and meta-analysis
LS prevalence among patients with UTUC is similar to that among patients with colorectal and endometrial cancers, which provides a strong rationale for LS testing in this population. Further research is necessary to determine the optimal diagnostic strategy.
Authors
- Joseph Moryousef (ORCID: https://orcid.org/0000-0003-0131-918X)
- Piotr Zareba
- Braden Millan
Institutions
- National Cancer Institute (US)
- Hamilton Health Sciences (CA)
- McMaster University (CA)
Publication Details
- Journal
- Urologic Oncology Seminars and Original Investigations
- Published
- 2026-02-10
- DOI
- https://doi.org/10.1016/j.urolonc.2026.110999
- Primary Topic
- Genetic factors in colorectal cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00