Mercury in the Needle: A Case of Malicious Injection and Toxicity

Intentional or accidental injection of mercury into soft tissue is rare. Mercury toxicity typically arises from ingestion or inhalation with instances of subcutaneous injection documented in a limited number of case studies. Most reported cases involve either accidental exposure or deliberate acts, often presenting as painful granulomas, with systemic symptoms a rarity. We present a compelling case involving a 39-year-old woman who developed a localized, painful gluteal lesion filled with mercury following multiple injections of what were purported to be multivitamin ampoules, administered by her ex-husband, a healthcare professional. Remarkably, the patient exhibited a serum mercury level of 345 μg/L without significant systemic manifestations which decreased after a course of treatment with succimer. This report highlights one of the rarest, if not the only documented instance of mercury toxicity caused by subcutaneous injection, potentially with homicidal intent.

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Publication Details

Journal
Clinical Case Reports
Published
2026-02-01
DOI
https://doi.org/10.1002/ccr3.71992
Primary Topic
Mercury impact and mitigation studies
Type
article
Field-Weighted Citation Impact
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article

Mercury in the Needle: A Case of Malicious Injection and Toxicity

Faraz Zandiyeh, Naghmeh Kian, Peyman Erfantalab Evini, Babak Mostafazadeh et al.
Clinical Case Reports
Mercury impact and mitigation studies
article

Mercury in the Needle: A Case of Malicious Injection and Toxicity

Faraz Zandiyeh, Naghmeh Kian, Peyman Erfantalab Evini, Babak Mostafazadeh, Mitra Rahimi, Shahin Shadnia
article en

Abstract

Intentional or accidental injection of mercury into soft tissue is rare. Mercury toxicity typically arises from ingestion or inhalation with instances of subcutaneous injection documented in a limited number of case studies. Most reported cases involve either accidental exposure or deliberate acts, often presenting as painful granulomas, with systemic symptoms a rarity. We present a compelling case involving a 39-year-old woman who developed a localized, painful gluteal lesion filled with mercury following multiple injections of what were purported to be multivitamin ampoules, administered by her ex-husband, a healthcare professional. Remarkably, the patient exhibited a serum mercury level of 345 μg/L without significant systemic manifestations which decreased after a course of treatment with succimer. This report highlights one of the rarest, if not the only documented instance of mercury toxicity caused by subcutaneous injection, potentially with homicidal intent.

Clinical Case ReportsVol. 14(2)
Shahid Beheshti University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 64%
Mercury impact and mitigation studies
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