Re‐evaluating the diagnostic value of α‐fetoprotein for hepatocellular carcinoma in the direct‐acting antiviral era

In the current era, lower baseline AFP levels are associated with improved diagnostic performance of AFP for HCC. Adoption of a 5 ng/mL AFP cutoff and 40 mAU/mL DCP cutoff appears appropriate for current clinical practice.

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Publication Details

Journal
Cancer
Published
2026-02-10
DOI
https://doi.org/10.1002/cncr.70308
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

Re‐evaluating the diagnostic value of α‐fetoprotein for hepatocellular carcinoma in the direct‐acting antiviral era

Yoshihiro Mise, Yoshinori Takeda, Ryuji Yoshioka, Hiroshi Imamura et al.
Cancer
Hepatocellular Carcinoma Treatment and Prognosis
article

Re‐evaluating the diagnostic value of α‐fetoprotein for hepatocellular carcinoma in the direct‐acting antiviral era

Yoshihiro Mise, Yoshinori Takeda, Ryuji Yoshioka, Hiroshi Imamura, Akio Saiura
article en

Abstract

In the current era, lower baseline AFP levels are associated with improved diagnostic performance of AFP for HCC. Adoption of a 5 ng/mL AFP cutoff and 40 mAU/mL DCP cutoff appears appropriate for current clinical practice.

CancerVol. 132(4)
Juntendo University (JP)
Good health and well-being
Openalex Percentile: Top 60%
Hepatocellular Carcinoma Treatment and Prognosis
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Re‐evaluating the diagnostic value of α‐fetoprotein for hepatocellular carcinoma in the direct‐acting antiviral era — Yoshihiro Mise, Yoshinori Takeda, et al. · Cancer (2026) | TGRS Research Map | TGRS