Concurrent Retinoblastoma 1 ( <i>RB1</i> ) and <i>IKZF1</i> Deletions Have Adverse Outcome in Childhood B‐Cell Acute Lymphoblastic Leukemia (B‐ALL)

The B-ALL patients with concurrent RB1 and IKZF1 deletions had worse outcomes compared to cases without any of these deletions. The RB1 deletion increased the risk of early events in patients with the IKZF1plus profile.

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Publication Details

Journal
International Journal of Laboratory Hematology
Published
2026-02-10
DOI
https://doi.org/10.1111/ijlh.70069
Primary Topic
Acute Lymphoblastic Leukemia research
Type
article
Field-Weighted Citation Impact
0.00
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article

Concurrent Retinoblastoma 1 ( RB1 ) and IKZF1 Deletions Have Adverse Outcome in Childhood B‐Cell Acute Lymphoblastic Leukemia (B‐ALL)

D. Pushpam, S. Bakhshi, Pranay Sharma, Gadha K. Leons et al.
International Journal of Laboratory Hematology
Acute Lymphoblastic Leukemia research
article

Concurrent Retinoblastoma 1 ( RB1 ) and IKZF1 Deletions Have Adverse Outcome in Childhood B‐Cell Acute Lymphoblastic Leukemia (B‐ALL)

D. Pushpam, S. Bakhshi, Pranay Sharma, Gadha K. Leons, Seema Gupta, Ritu Gupta, Smeeta Gajendra
article en

Abstract

The B-ALL patients with concurrent RB1 and IKZF1 deletions had worse outcomes compared to cases without any of these deletions. The RB1 deletion increased the risk of early events in patients with the IKZF1plus profile.

International Journal of Laboratory Hematology
All India Institute of Medical Sciences (IN)
Openalex Percentile: Top 63%
Acute Lymphoblastic Leukemia research
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