Microfluidic innovations in chronic kidney disease and renal fibrosis: from mechanistic insights to clinical applications

Microfluidic technologies bridge the gap between bench and bedside by enabling mechanistic discovery, sensitive biomarker detection, and translational therapeutic testing in CKD and fibrosis. Despite significant advances, challenges remain in scalability, reproducibility, and regulatory approval. Addressing these hurdles through interdisciplinary collaboration will be essential. With continued innovation, microfluidic systems hold strong promise for advancing precision nephrology and improving patient outcomes.