Fuzheng Jiedu Formula Ameliorates Acute Lung Injury by Modulating Gut Microbiota to Enhance Short-Chain Fatty Acid

Our results imply that FZJDF could exert its palliative effect in ALI by regulating the intestinal microbiota to increase the production of SCFAs, which in turn inhibits neutrophil-mediated inflammatory responses. These findings support microbiota-targeted traditional medicine as a translational strategy for acute lung injury.

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Publication Details

Journal
Journal of Inflammation Research
Published
2026-02-01
DOI
https://doi.org/10.2147/jir.s556752
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00
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article

Fuzheng Jiedu Formula Ameliorates Acute Lung Injury by Modulating Gut Microbiota to Enhance Short-Chain Fatty Acid

Jiankun Chen, Zhaoqi Tan, Kao Gan, Ming Gao et al.
Journal of Inflammation Research
Gut microbiota and health
article

Fuzheng Jiedu Formula Ameliorates Acute Lung Injury by Modulating Gut Microbiota to Enhance Short-Chain Fatty Acid

Jiankun Chen, Zhaoqi Tan, Kao Gan, Ming Gao, Meng Zhao, Yue Lu, Yunqi Kong, Wanhua Huo, Simin Pan, Rongyuan Yang, Yuan Wu, Yue Lu, Qinghua Xia, Chubo Yin, Yuntao Liu
article en

Abstract

Our results imply that FZJDF could exert its palliative effect in ALI by regulating the intestinal microbiota to increase the production of SCFAs, which in turn inhibits neutrophil-mediated inflammatory responses. These findings support microbiota-targeted traditional medicine as a translational strategy for acute lung injury.

Journal of Inflammation ResearchVol. Volume 19
Guangzhou University of Chinese Medicine (CN), Integrated Chinese Medicine (China) (HK), Xiyuan Hospital (CN)
Good health and well-being
Openalex Percentile: Top 62%
Gut microbiota and health
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