Comorbid HIV and Cocaine Use Exacerbate Accelerated Brain Aging
Comorbid HIV/CU is linked to accelerated structural brain aging. BAG may reflect brain-level alterations underlying the association between comorbid HIV/CU and cognitive impairment, and may help identify network-specific targets for intervention.
Authors
- Shenghan Lai
- Hui Zheng (ORCID: https://orcid.org/0000-0003-3085-4560)
- Hong Lai (ORCID: https://orcid.org/0000-0003-2918-2381)
- Yihong Yang
- Betty Jo Salmeron
- Danni Wang
- Hong Gu
- Nanyu Kuang
Institutions
- University of Maryland, Baltimore (US)
- National Institutes of Health (US)
- National Institute on Drug Abuse (US)
- Johns Hopkins University (US)
- Johns Hopkins Medicine (US)
Publication Details
- Journal
- bioRxiv (Cold Spring Harbor Laboratory)
- Published
- 2026-02-09
- DOI
- https://doi.org/10.64898/2026.02.06.704435
- Primary Topic
- HIV Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Health and Human Services
- National Institutes of Health
- McDonnell Center for Systems Neuroscience