Efficacy and Safety of Ciprofol for Sedation in Critically Ill Patients After Cardiac Surgery: A Single-Center, Prospective, Randomized Controlled Trial

In summary, ciprofol provides non-inferior sedation efficacy and a comparable safety profile to propofol in critically ill patients following cardiac surgery. A numerical trend toward lower hypotension incidence was observed with ciprofol, which warrants further validation in future studies.

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Publication Details

Journal
Drug Design Development and Therapy
Published
2026-02-01
DOI
https://doi.org/10.2147/dddt.s568956
Primary Topic
Anesthesia and Sedative Agents
Type
article
Field-Weighted Citation Impact
0.00
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article

Efficacy and Safety of Ciprofol for Sedation in Critically Ill Patients After Cardiac Surgery: A Single-Center, Prospective, Randomized Controlled Trial

Yongshuai Li, Min Hong, Jiaqiong Li, Wenjing Du et al.
Drug Design Development and Therapy
Anesthesia and Sedative Agents
article

Efficacy and Safety of Ciprofol for Sedation in Critically Ill Patients After Cardiac Surgery: A Single-Center, Prospective, Randomized Controlled Trial

Yongshuai Li, Min Hong, Jiaqiong Li, Wenjing Du, Pingping Li, Lulu Guo
article en

Abstract

In summary, ciprofol provides non-inferior sedation efficacy and a comparable safety profile to propofol in critically ill patients following cardiac surgery. A numerical trend toward lower hypotension incidence was observed with ciprofol, which warrants further validation in future studies.

Drug Design Development and TherapyVol. Volume 20
Xuzhou Medical College (CN), Xuzhou Central Hospital (CN)
Good health and well-being
Openalex Percentile: Top 60%
Anesthesia and Sedative Agents
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