Increased risk of incident dementia associated with vitamin D deficiency in glaucoma patients: a TriNetX cohort study

VDD is significantly associated with an increased risk of developing dementia in patients with glaucoma. These time-dependent and dose-response findings raise the possibility that correcting vitamin D deficiency may influence neurodegenerative outcomes, additional prospective studies are required to establish causality and clarify clinical implications.

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Publication Details

Journal
Frontiers in Nutrition
Published
2026-02-10
DOI
https://doi.org/10.3389/fnut.2026.1760959
Primary Topic
Glaucoma and retinal disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Increased risk of incident dementia associated with vitamin D deficiency in glaucoma patients: a TriNetX cohort study

Chien-Lin Lu, Kuo-Cheng Lu, Ming Ling Tsai, Yu-Chen Cheng et al.
Frontiers in Nutrition
Glaucoma and retinal disorders
article

Increased risk of incident dementia associated with vitamin D deficiency in glaucoma patients: a TriNetX cohort study

Chien-Lin Lu, Kuo-Cheng Lu, Ming Ling Tsai, Yu-Chen Cheng, Joshua Wang
article en

Abstract

VDD is significantly associated with an increased risk of developing dementia in patients with glaucoma. These time-dependent and dose-response findings raise the possibility that correcting vitamin D deficiency may influence neurodegenerative outcomes, additional prospective studies are required to establish causality and clarify clinical implications.

Frontiers in NutritionVol. 13
Fu Jen Catholic University (TW), Queensland University of Technology (AU), Taipei Tzu Chi Hospital (TW), Buddhist Tzu Chi Medical Foundation (US)
Buddhist Tzu Chi Medical Foundation, Taipei Tzu Chi Hospital, Fu Jen Catholic University
Good health and well-being
Openalex Percentile: Top 61%
Glaucoma and retinal disorders
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