Xing-Pi-Qing-Gan decoction alleviates alcoholic liver disease by down-regulating <i>DDIT3</i> and restoring <i>Nrf2</i> / <i>HO-1</i> antioxidant signaling: Multi-omics and experimental evidence
In summary, the results of the study suggest that XPQG is effective in improving ethanol-induced acute liver injury (ALD). Its mechanism involves the suppression of <i>DDIT3</i> and the enhancement of <i>Nrf2</i>/<i>HO-1</i> pathway activity.
Authors
- Xiaoyan Feng (ORCID: https://orcid.org/0000-0002-5239-9362)
- Yi Zheng
- Yu-Jie Xu
- Tao Sun
- Na-Fei Huang
- Ping Ling
Institutions
- Zhejiang Chinese Medical University (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
Publication Details
- Journal
- World Journal of Gastroenterology
- Published
- 2026-02-10
- DOI
- https://doi.org/10.3748/wjg.v32.i8.115077
- Primary Topic
- Alcohol Consumption and Health Effects
- Type
- article
- Field-Weighted Citation Impact
- 0.00