SIRT1 rs7069102 Polymorphism Confers Increased Risk of Diabetic Retinopathy in T2DM
A significant difference in the distribution of <i>SIRT1</i> rs7069102 genotypes and alleles was observed between the groups. Under the dominant inheritance model, patients with CC or CG genotypes were more likely to develop DR than those with the GG genotype (OR = 1.30; 95% CI = 1.02-1.65; <i>p</i> = 0.036). No significant association was found between <i>TNF-α</i> rs1800629 and DR.
Authors
- Daniel Petrovič (ORCID: https://orcid.org/0000-0001-6637-2542)
- Globocnik Petrovic M
- Jernej Letonja (ORCID: https://orcid.org/0000-0002-1473-3534)
- Ema Šuligoj
- Melina Bešić
- Stella Stare
- Ana Peterlin
Institutions
- University of Ljubljana (SI)
- Ljubljana University Medical Centre (SI)
Publication Details
- Journal
- Genes
- Published
- 2026-02-10
- DOI
- https://doi.org/10.3390/genes17020221
- Primary Topic
- Sirtuins and Resveratrol in Medicine
- Type
- article
- Field-Weighted Citation Impact
- 0.00