Association between leukocyte telomere length and neurodegenerative diseases: a prospective cohort in the UK Biobank
Shorter LTL increased the risk of several NDDs, while longer LTL paradoxically predisposed individuals to MS, especially in younger populations. ML models demonstrated strong potential for predicting NDD risks, enhancing our understanding of the role of telomeres in neurodegeneration.
Authors
- Min Huang
- Xiangting Chen
- Yueqing Huang
- Chunhua Zhao
Institutions
- Suzhou Municipal Hospital (CN)
Publication Details
- Journal
- Journal of Neurology
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1007/s00415-025-13479-1
- Primary Topic
- Telomeres, Telomerase, and Senescence
- Type
- article
- Field-Weighted Citation Impact
- 0.00