Ferrostatin-1 attenuates sepsis-induced lung injury by inhibiting ferroptosis via activation of the SLC7A11/GSH/GPX4 signaling pathway
In sepsis-induced lung injury, the ferroptosis-related SLC7A11/GSH/GPX4 signaling pathway is downregulated. Ferrostatin-1 activates this pathway and protects the lungs.
Authors
- Jiahui Zheng (ORCID: https://orcid.org/0000-0003-3758-9149)
- Peiwu Li (ORCID: https://orcid.org/0000-0003-2671-7811)
- Hongyao Li
- Haidan Zhang
- Shixian Liu
Institutions
- Lanzhou University Second Hospital (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Journal of Chromatography B
- Published
- 2026-02-09
- DOI
- https://doi.org/10.1016/j.jchromb.2026.124962
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00