Why It Is Unethical <i>Not</i> to Conduct Randomized Trials in Pregnancy

This Viewpoint discusses the need to develop systematic review processes for medications during pregnancy, including routine randomized clinical trials (RCTs), rather than relying on observational study data.

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Publication Details

Journal
JAMA
Published
2026-02-09
DOI
https://doi.org/10.1001/jama.2026.0805
Primary Topic
Pregnancy and Medication Impact
Type
article
Field-Weighted Citation Impact
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article

Why It Is Unethical Not to Conduct Randomized Trials in Pregnancy

Alyssa Bilinski
JAMA
Pregnancy and Medication Impact
article

Why It Is Unethical Not to Conduct Randomized Trials in Pregnancy

Alyssa Bilinski
article en

Abstract

This Viewpoint discusses the need to develop systematic review processes for medications during pregnancy, including routine randomized clinical trials (RCTs), rather than relying on observational study data.

JAMAVol. 335(12)
Rhode Island Department of Health (US), Brown University (US), Department of Health Services (NP)
Openalex Percentile: Top 64%
Pregnancy and Medication Impact
DOISourceOpenAlex
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Why It Is Unethical <i>Not</i> to Conduct Randomized Trials in Pregnancy — Alyssa Bilinski · JAMA (2026) | TGRS Research Map | TGRS