Volumetric signatures of basal ganglia–thalamo–cortical and cerebello–thalamo–cortical networks in Parkinson's disease and its motor subtypes

Multiregional volumetric analysis within the BTC and CTC motor networks uncovered group differences between PD and HC that were not apparent when examining single ROIs alone. These findings highlight that PD-related alterations manifest as distributed volumetric patterns across interconnected motor circuits, supporting their role as imaging biomarkers.