A Clinician’s Guide for Trending Cardiovascular Nutritional Controversies in 2026
Although the broad outlines of a healthy diet are clear, controversy has arisen surrounding certain foods and nutrients. This review updates contemporary nutrition controversies and the extent to which they may promote or protect against cardiovascular disease (CVD). In this review, beef tallow, ultraprocessed foods, full-fat dairy, seed oils, medium chain triglyceride oils, seafood, and alternative sweeteners are considered. Three groupings included: 1) evidence of harm with a recommendation to limit or avoid; 2) lacking in evidence for harm or benefit; and 3) evidence of benefit. The evidence of harm category included beef tallow, due to association with increased low-density lipoprotein cholesterol, ultraprocessed foods associated with worsened cardiometabolic health, and artificial sweeteners owing to correlations with increased CVD. Within the category lacking in evidence were full-fat dairy, medium chain triglyceride, monk fruit, and stevia. Finally, evidence of benefit included seed oils and seafood based on improved CVD outcomes.
Authors
- Monica Aggarwal (ORCID: https://orcid.org/0000-0002-7027-0060)
- Elizabeth Klodas (ORCID: https://orcid.org/0000-0002-3667-642X)
- Kathleen Allen (ORCID: https://orcid.org/0000-0001-9518-4487)
- Robert J. Ostfeld
- Dariush Mozaffarian
- Romit Bhattacharya
- Lily N. Dastmalchi
- Koushik R. Reddy
- Michael Miller
- Andrew M. Freeman
- Kristina S. Petersen
- Emilio Ros
- Penny M. Kris-Etherton
- Vall Vinaithirthan
Institutions
- Inova Health System (US)
- Tufts University (US)
- Pennsylvania State University (US)
- National Jewish Health (US)
- University of Florida (US)
- Massachusetts General Hospital (US)
- James A. Haley Veterans' Hospital (US)
- Montefiore Health System (US)
- Philadelphia VA Medical Center (US)
- Land Stewardship Project (US)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- University of Colorado Denver (US)
Publication Details
- Journal
- JACC Advances
- Published
- 2026-02-09
- DOI
- https://doi.org/10.1016/j.jacadv.2026.102591
- Primary Topic
- Nutritional Studies and Diet
- Type
- article
- Field-Weighted Citation Impact
- 0.00