Fatal refractory chronic active Epstein-Barr virus infection with hemophagocytic lymphohistiocytosis and NK/T-cell lymphoma: a case report

CAEBV is a rare and fatal complication of EBV. Clinician education, early recognition, and expert consultation improve outcomes. Treatment so far consists of chemotherapy followed by hematopoietic stem cell transplantation.

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Publication Details

Journal
ASM Case Reports
Published
2026-02-09
DOI
https://doi.org/10.1128/asmcr.00168-25
Primary Topic
Autoimmune and Inflammatory Disorders Research
Type
article
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0.00
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article

Fatal refractory chronic active Epstein-Barr virus infection with hemophagocytic lymphohistiocytosis and NK/T-cell lymphoma: a case report

Rima El-Herte, Nicholas Mielke, Marlaena Nicole Nooney, Nagendra Natarajan
ASM Case Reports
Autoimmune and Inflammatory Disorders Research
article

Fatal refractory chronic active Epstein-Barr virus infection with hemophagocytic lymphohistiocytosis and NK/T-cell lymphoma: a case report

Rima El-Herte, Nicholas Mielke, Marlaena Nicole Nooney, Nagendra Natarajan
article en

Abstract

CAEBV is a rare and fatal complication of EBV. Clinician education, early recognition, and expert consultation improve outcomes. Treatment so far consists of chemotherapy followed by hematopoietic stem cell transplantation.

ASM Case ReportsVol. 2(2)
Creighton University (US), Nebraska Cancer Specialists (US)
Good health and well-being
Openalex Percentile: Top 60%
Autoimmune and Inflammatory Disorders Research
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Fatal refractory chronic active Epstein-Barr virus infection with hemophagocytic lymphohistiocytosis and NK/T-cell lymphoma: a case report — Rima El-Herte, Nicholas Mielke, et al. · ASM Case Reports (2026) | TGRS Research Map | TGRS