Protocol of a multi-centre randomized controlled trial to compare pericapsular nerve group block, fascia-iliaca compartment block and femoral nerve block for pain management in patients with a hip fracture in the emergency department (CPFF-ED)

This randomized controlled trial with a superiority design will allow conclusions on which regional nerve block is most effective in improving pre-operative wellbeing in patients with a neck of femur or pertrochanteric fracture. The choice to use a patient reported outcome measure to evaluate block efficacy maximizes clinical relevance. And by allowing the choice of local anaesthetic to the participating hospital (with a 1:1:1 randomization for each participating centre) clinical applicability of our findings is maximized.