Time to Cross Paths: Neuroplasticity-Informed ACL Rehabilitation that Includes Cross-Education
The efficacy of anterior cruciate ligament (ACL) rehabilitation following reconstruction surgery is sub-optimal and the return-to-sport criteria are inconsistent. We examine the hypothesis that the dysfunctional neuroplasticity induced by an ACL injury could be resolved faster when cross-education is combined with innovative paradigms incorporating visual-cognitive tasks to reduce attentional compensation. We posit that the priming effects could be amplified if therapists combined higher force, eccentric based cross-education exercises with visual-cognitive dual-tasking. The overlapping nature of neuroplasticity after an ACL injury and that induced by cross education may provide a pathway to not only address the mechanical muscle strength deficits associated with injury, but the underlying neurological deficits as well. We provide a practical guide to how neuroplasticity-informed ACL rehabilitation that includes cross-education might accelerate recovery from an ACL injury and the subsequent reconstruction surgery.
Authors
- Justin W. Andrushko (ORCID: https://orcid.org/0000-0003-2258-1689)
- Márk Váczi (ORCID: https://orcid.org/0000-0002-7047-7088)
- Jonathan P. Farthing (ORCID: https://orcid.org/0000-0002-2549-1227)
- Tibor Mintál
- Dustin R. Grooms (ORCID: https://orcid.org/0000-0001-6102-8224)
- Nicola A. Maffiuletti
- Leila Bogdán
- Gergely Orsi
- Tibor Hortobágyi
- Rubén Lara Gómez
Institutions
- University Medical Center Groningen (NL)
- Northumbria University (GB)
- University of Saskatchewan (CA)
- Ohio University (US)
- Schulthess-Klinik (CH)
- Hungarian School Sport Federation (HU)
- Andalusian Centre for Nanomedicine and Biotechnology (ES)
- Instituto de Investigación Biomédica de Málaga (ES)
- University of Pecs (HU)
- Universidad de Málaga (ES)
Publication Details
- Journal
- Sports Medicine - Open
- Published
- 2026-02-09
- DOI
- https://doi.org/10.1186/s40798-025-00967-x
- Primary Topic
- Knee injuries and reconstruction techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Hungarian Scientific Research Fund
- National Research, Development and Innovation Office