1-Nitropyrene induces acute lung injury via SYVN1/Caspase-11-mediated apoptosis and pyroptosis in pulmonary epithelial cells
These results revealed that acute 1-NP may induce ALI via Caspase-11-mediated apoptosis and pyroptosis by downregulating SYVN1.
Authors
- Dong-Xu Hua (ORCID: https://orcid.org/0009-0008-9919-2888)
- Hongyun Zhao (ORCID: https://orcid.org/0000-0002-1251-3888)
- Chuan-mei Liu (ORCID: https://orcid.org/0000-0002-9959-3832)
- Ruixue Wang (ORCID: https://orcid.org/0000-0002-8772-4954)
- Lu Xiu (ORCID: https://orcid.org/0009-0002-2759-8201)
- Min-Min Tang
- Lin Fu
- Zhao-Lei Ding
- Yi-Chen Ma
- Ling Zheng
Institutions
- Weifang Medical University (CN)
- Anhui Medical University (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2026-02-09
- DOI
- https://doi.org/10.3389/fphar.2026.1723593
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- University Natural Science Research Project of Anhui Province