The Role of COL1A1, COL5A1, ACTN3, MMP3, and GDF5 Gene Variants in Common Sports Injuries: Systematic Review of ACL Rupture, Achilles Tendinopathy, and Stress Fractures
Genetic variants in <i>COL1A1</i>, <i>COL5A1</i>, <i>MMP3</i>, <i>ACTN3</i>, and <i>GDF5</i> may influence susceptibility to ACL rupture, Achilles tendinopathy, and stress fractures. Larger, multi-ethnic studies are needed to validate these findings and inform personalised injury prevention strategies.
Authors
- David John Hunter (ORCID: https://orcid.org/0000-0003-1060-3334)
- Sarabjit Mastana (ORCID: https://orcid.org/0000-0002-9553-4886)
- Elizabeth C. Akam (ORCID: https://orcid.org/0000-0002-8784-3742)
- Shahd Abboud
Institutions
- Loughborough University (GB)
Publication Details
- Journal
- Genes
- Published
- 2026-02-09
- DOI
- https://doi.org/10.3390/genes17020212
- Primary Topic
- Tendon Structure and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00