Predictive Value of Placental Growth Factor and Soluble FMS-Like Tyrosine Kinase-1 Detection in Early Pregnancy for Gestational Diabetes Mellitus: A Case-Control Study

Lower PIGF and higher sFlt-1 levels in early pregnancy may be associated with GDM development and adverse outcomes. These biomarkers demonstrate potential predictive value, but large-scale prospective studies are required to confirm clinical utility.

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Publication Details

Journal
International Journal of Women s Health
Published
2026-02-01
DOI
https://doi.org/10.2147/ijwh.s542217
Primary Topic
Gestational Diabetes Research and Management
Type
article
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article

Predictive Value of Placental Growth Factor and Soluble FMS-Like Tyrosine Kinase-1 Detection in Early Pregnancy for Gestational Diabetes Mellitus: A Case-Control Study

Xinli Liu, Wen Wu
International Journal of Women s Health
Gestational Diabetes Research and Management
article

Predictive Value of Placental Growth Factor and Soluble FMS-Like Tyrosine Kinase-1 Detection in Early Pregnancy for Gestational Diabetes Mellitus: A Case-Control Study

Xinli Liu, Wen Wu
article en

Abstract

Lower PIGF and higher sFlt-1 levels in early pregnancy may be associated with GDM development and adverse outcomes. These biomarkers demonstrate potential predictive value, but large-scale prospective studies are required to confirm clinical utility.

International Journal of Women s HealthVol. Volume 18
Central South University (CN), Third Xiangya Hospital (CN)
Good health and well-being
Openalex Percentile: Top 64%
Gestational Diabetes Research and Management
DOIOpen Access PDFOpenAlex
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Predictive Value of Placental Growth Factor and Soluble FMS-Like Tyrosine Kinase-1 Detection in Early Pregnancy for Gestational Diabetes Mellitus: A Case-Control Study — Xinli Liu, Wen Wu · International Journal of Women s Health (2026) | TGRS Research Map | TGRS