The role of lncRNA-associated ceRNA networks in yak longissimus dorsi muscle development across feeding systems

Our findings suggest that intensive feeding modulates yak muscle growth and tenderness through IncRNA-mediated pathways involved in metabolic adaptation and extracellular matrix remodeling. The identified TCONS_00010840-miR - 30b - 5p- TRIM63 and TCONS_00013998-ADAMTS2 regulatory nodes represent potential molecular targets for improving yak meat quality. These results provide a theoretical framework for future functional studies into the molecular breeding of yaks.

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Publication Details

Journal
BMC Veterinary Research
Published
2026-02-09
DOI
https://doi.org/10.1186/s12917-026-05312-2
Primary Topic
Cancer-related molecular mechanisms research
Type
article
Field-Weighted Citation Impact
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article

The role of lncRNA-associated ceRNA networks in yak longissimus dorsi muscle development across feeding systems

Yongfu La, Pengjia Bao, Ping Yan, Xian Guo et al.
BMC Veterinary Research
Cancer-related molecular mechanisms research
article

The role of lncRNA-associated ceRNA networks in yak longissimus dorsi muscle development across feeding systems

Yongfu La, Pengjia Bao, Ping Yan, Xian Guo, Tong Wang, Min Chu, Jianbin Liu, Chunnian Liang, Xiaoming Ma, Xiaoyun Wu
article en

Abstract

Our findings suggest that intensive feeding modulates yak muscle growth and tenderness through IncRNA-mediated pathways involved in metabolic adaptation and extracellular matrix remodeling. The identified TCONS_00010840-miR - 30b - 5p- TRIM63 and TCONS_00013998-ADAMTS2 regulatory nodes represent potential molecular targets for improving yak meat quality. These results provide a theoretical framework for future functional studies into the molecular breeding of yaks.

BMC Veterinary ResearchVol. 22(1)
Lanzhou Institute of Husbandry and Pharmaceutical Sciences (CN), Ministry of Agriculture (CA), Chinese Academy of Agricultural Sciences (CN), Ministry of Agriculture and Rural Affairs (CN)
Zero hunger
Openalex Percentile: Top 63%
Cancer-related molecular mechanisms research
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