Correlation Between MRI T2 Hyperintensity, Apoptosis, and Neuroinflammation in Chronic Cervical Spinal Cord Compression
In chronic cervical spinal cord compression, MRI T2 hyperintensity correlates significantly with the severity of neuronal apoptosis and NLRP3-mediated neuroinflammation, suggesting that SCR may serve as a quantitative imaging biomarker for underlying pathological changes in DCM.
Authors
- X L Zhang (ORCID: https://orcid.org/0009-0001-0842-935X)
- Duo Zhang (ORCID: https://orcid.org/0000-0001-9011-4316)
- Bingxuan Wu
- Baoge Liu
- Tianhua Rong
- Qinghua Sang
- Peng Zhao
Institutions
- Beijing Tian Tan Hospital (CN)
- Beijing Fengtai Hospital (CN)
- Yueqing People's Hospital (CN)
Publication Details
- Journal
- Spine
- Published
- 2026-02-05
- DOI
- https://doi.org/10.1097/brs.0000000000005640
- Primary Topic
- Cervical and Thoracic Myelopathy
- Type
- article
- Field-Weighted Citation Impact
- 0.00