A Head-to-Head Comparison of AAV9 Biodistribution in Mice: Routes of Administration and Age Dependence

Our results provide the necessary biodistribution data to establish a standardized benchmark for comparison of the current gold standard AAV9 to next generation viral vectors. Additionally, this body of work can provide valuable insights for the design of translational gene therapy studies.

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Publication Details

Journal
Genes
Published
2026-02-09
DOI
https://doi.org/10.3390/genes17020213
Primary Topic
Virus-based gene therapy research
Type
article
Field-Weighted Citation Impact
0.00
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article

A Head-to-Head Comparison of AAV9 Biodistribution in Mice: Routes of Administration and Age Dependence

S. Gray, Andrea Boitnott, Satvik R Paduri, Yuhui Hu et al.
Genes
Virus-based gene therapy research
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A Head-to-Head Comparison of AAV9 Biodistribution in Mice: Routes of Administration and Age Dependence

S. Gray, Andrea Boitnott, Satvik R Paduri, Yuhui Hu, Matthew Rioux
article en

Abstract

Our results provide the necessary biodistribution data to establish a standardized benchmark for comparison of the current gold standard AAV9 to next generation viral vectors. Additionally, this body of work can provide valuable insights for the design of translational gene therapy studies.

GenesVol. 17(2)
Southwestern Medical Center (US), Southwestern Medical Center (US), The University of Texas Southwestern Medical Center (US)
Openalex Percentile: Top 59%
Virus-based gene therapy research
DOIOpen Access PDFOpenAlex
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