ECRG4 suppressed the progression of breast cancer via modulating NFIC/PTEN and SHP2/PI3K/SP1 signaling

ECRG4 inhibits breast cancer progression by positively regulating NFIC/PTEN to suppress the SHP2/PI3K/SP1 signaling pathway. Targeting this signaling axis may provide a new strategy for breast cancer treatment.

Authors

Dianbin Ning
Xinyu Zhao (ORCID: https://orcid.org/0000-0002-5128-4424)
Yusen Wei
Dan Song

Institutions

Hebei General Hospital (CN)

Publication Details

Journal: European journal of medical research
Published: 2026-02-09
DOI: https://doi.org/10.1186/s40001-026-04009-4
Primary Topic: Chromatin Remodeling and Cancer
Type: article
Field-Weighted Citation Impact: 0.00

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article

ECRG4 suppressed the progression of breast cancer via modulating NFIC/PTEN and SHP2/PI3K/SP1 signaling

Dianbin Ning, Xinyu Zhao, Yusen Wei, Dan Song

Feb 9, 2026

European journal of medical research

Chromatin Remodeling and Cancer

article

ECRG4 suppressed the progression of breast cancer via modulating NFIC/PTEN and SHP2/PI3K/SP1 signaling

Dianbin Ning, Xinyu Zhao, Yusen Wei, Dan Song

February 9, 2026article en

Abstract

European journal of medical researchVol. 31(1)

Hebei General Hospital (CN)

Good health and well-being

Openalex Percentile: Top 62%

Chromatin Remodeling and Cancer

DOI Open Access PDF OpenAlex

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ECRG4 suppressed the progression of breast cancer via modulating NFIC/PTEN and SHP2/PI3K/SP1 signaling — Dianbin Ning, Xinyu Zhao, et al. · European journal of medical research (2026) | TGRS Research Map | TGRS