Management of Ischemia and Necrosis Following Nonsurgical Rhinoplasty With Hyaluronic Acid: A Case Report

Nonsurgical rhinoplasty with hyaluronic acid (HA) is minimally invasive but may result in severe vascular complications such as ischemia and necrosis. This case report describes a 30-year-old female patient who developed ischemia and early necrosis of the nasal tip after HA injection. Treatment was initiated approximately 72 hours after the injection, and management included multipoint hyaluronidase, massage and warm compresses, low-level red laser therapy, systemic antibiotic and corticosteroid administration, in addition to hyperbaric oxygen therapy and photodynamic therapy. Regression of ischemia was observed on the first day after treatment initiation, and complete re-epithelialization occurred within 26 days. Early diagnosis and multimodal management centered on hyaluronidase favored ischemia reversal and wound healing, minimizing sequelae.

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Journal
Cureus
Published
2026-02-09
DOI
https://doi.org/10.7759/cureus.103290
Primary Topic
Facial Rejuvenation and Surgery Techniques
Type
article
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article

Management of Ischemia and Necrosis Following Nonsurgical Rhinoplasty With Hyaluronic Acid: A Case Report

Andrea Tedesco, Alan Cristian Marinho Ferreira, Sabrina C Pacheco, Antony P Barbosa et al.
Cureus
Facial Rejuvenation and Surgery Techniques
article

Management of Ischemia and Necrosis Following Nonsurgical Rhinoplasty With Hyaluronic Acid: A Case Report

Andrea Tedesco, Alan Cristian Marinho Ferreira, Sabrina C Pacheco, Antony P Barbosa, Francine F Posser Ribeiro, Anna Clara C Commanducci Silva, Roberta G Neves, Ithala L Oliveira Parpinelli
article en

Abstract

Nonsurgical rhinoplasty with hyaluronic acid (HA) is minimally invasive but may result in severe vascular complications such as ischemia and necrosis. This case report describes a 30-year-old female patient who developed ischemia and early necrosis of the nasal tip after HA injection. Treatment was initiated approximately 72 hours after the injection, and management included multipoint hyaluronidase, massage and warm compresses, low-level red laser therapy, systemic antibiotic and corticosteroid administration, in addition to hyperbaric oxygen therapy and photodynamic therapy. Regression of ischemia was observed on the first day after treatment initiation, and complete re-epithelialization occurred within 26 days. Early diagnosis and multimodal management centered on hyaluronidase favored ischemia reversal and wound healing, minimizing sequelae.

CureusVol. 18(2)
Universidade Federal do Rio de Janeiro (BR), Pontifícia Universidade Católica de Minas Gerais (BR), Anton Proksch Institut (AT), Nuclear Engineering Institute (BR), Universidade Federal do Estado do Rio de Janeiro (BR)
Good health and well-being
Openalex Percentile: Top 61%
Facial Rejuvenation and Surgery Techniques
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Management of Ischemia and Necrosis Following Nonsurgical Rhinoplasty With Hyaluronic Acid: A Case Report — Andrea Tedesco, Alan Cristian Marinho Ferreira, et al. · Cureus (2026) | TGRS Research Map | TGRS