The impact of statin use on colorectal cancer prognosis: a systematic review and meta-analysis

Statin use was associated with a reduction in ACM and CSM in CRC patients. However, the variances in RFS and DFS were not statistically significant. However, these findings should be interpreted cautiously due to substantial heterogeneity among some included studies.

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Publication Details

Journal
BMC Gastroenterology
Published
2026-02-09
DOI
https://doi.org/10.1186/s12876-025-04398-6
Primary Topic
Cancer, Lipids, and Metabolism
Type
article
Field-Weighted Citation Impact
0.00
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article

The impact of statin use on colorectal cancer prognosis: a systematic review and meta-analysis

Mostafa Neshat Ghalibaf, Parsa Tavassoli Naini, Maryam Shirmohamadi, Amir Hosein Shabani et al.
BMC Gastroenterology
Cancer, Lipids, and Metabolism
article

The impact of statin use on colorectal cancer prognosis: a systematic review and meta-analysis

Mostafa Neshat Ghalibaf, Parsa Tavassoli Naini, Maryam Shirmohamadi, Amir Hosein Shabani, Mahdiyeh Nozad Varjovi, Iman Elahi Vahed, Mohammad Rahmanian, Mohaddese Heydari, Amir mohammad Rishialiabad, Hossein Soltaninejad, Alireza Gholami, Mojtaba Esmaeeli, Fatemeh Moeinaddini, Asal Kazemzadeh, Mohammadsadegh Jafari
article en

Abstract

Statin use was associated with a reduction in ACM and CSM in CRC patients. However, the variances in RFS and DFS were not statistically significant. However, these findings should be interpreted cautiously due to substantial heterogeneity among some included studies.

BMC Gastroenterology
Isfahan University of Medical Sciences (IR), Tarbiat Modares University (IR), Tabriz University of Medical Sciences (IR), Shahid Sadoughi University of Medical Sciences and Health Services (IR), Universal Scientific Education and Research Network (IR), Research Institute for Endocrine Sciences (IR), Hormozgan University of Medical Sciences (IR), Islamic Azad University Kerman (IR), Sabzevar University of Medical Sciences (IR), Shahid Beheshti University of Medical Sciences (IR), Qazvin University of Medical Sciences (IR)
Good health and well-being
Openalex Percentile: Top 63%
Cancer, Lipids, and Metabolism
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The impact of statin use on colorectal cancer prognosis: a systematic review and meta-analysis — Mostafa Neshat Ghalibaf, Parsa Tavassoli Naini, et al. · BMC Gastroenterology (2026) | TGRS Research Map | TGRS