Biological evaluation of resin-modified glass ionomer cement containing coumarin derivatives for dental application

RMGIC incorporated with coumarin derivatives at 0.5 % exhibited the most favorable biological performance, achieving an optimal balance between cytotoxicity and antibacterial properties compared with concentrations of 1.0 % and 1.5 %. RMGIC-CT at 0.5 % appeared to be more effective than RMGIC-AC at 0.5 %, as shown by the stronger inhibition of <i>S. mutans</i>.

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Publication Details

Journal
Journal of Taibah University Medical Sciences
Published
2026-02-01
DOI
https://doi.org/10.1016/j.jtumed.2026.01.007
Primary Topic
Dental materials and restorations
Type
article
Field-Weighted Citation Impact
0.00
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article

Biological evaluation of resin-modified glass ionomer cement containing coumarin derivatives for dental application

Dasmawati Mohamad, Hasnah Osman, Fatimah S.A. Rahman, Nor A.F. Azlisham
Journal of Taibah University Medical Sciences
Dental materials and restorations
article

Biological evaluation of resin-modified glass ionomer cement containing coumarin derivatives for dental application

Dasmawati Mohamad, Hasnah Osman, Fatimah S.A. Rahman, Nor A.F. Azlisham
article en

Abstract

RMGIC incorporated with coumarin derivatives at 0.5 % exhibited the most favorable biological performance, achieving an optimal balance between cytotoxicity and antibacterial properties compared with concentrations of 1.0 % and 1.5 %. RMGIC-CT at 0.5 % appeared to be more effective than RMGIC-AC at 0.5 %, as shown by the stronger inhibition of <i>S. mutans</i>.

Journal of Taibah University Medical SciencesVol. 21(1)
Universiti Sains Malaysia (MY), Hospital Universiti Sains Malaysia (MY)
Openalex Percentile: Top 61%
Dental materials and restorations
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Biological evaluation of resin-modified glass ionomer cement containing coumarin derivatives for dental application — Dasmawati Mohamad, Hasnah Osman, et al. · Journal of Taibah University Medical Sciences (2026) | TGRS Research Map | TGRS