Prognostic value of PD-L1 expression on tumor-infiltrating immune cells and neutrophil-to-lymphocyte ratio in patients with biliary tract cancer
PD-L1 expression on TIICs and dynamic NLR may be indicative of prognosis in BTC and could provide insights into immune status and response to immunotherapy after recurrence. These findings highlight the potential value of integrating local immune contexture with systemic inflammatory markers, but further validation in larger and prospective cohorts is warranted.
Authors
- Xiaojun Lin
- Zehui Yao (ORCID: https://orcid.org/0000-0002-7590-1239)
- Gelun Huang (ORCID: https://orcid.org/0000-0001-9473-802X)
- Shang Chen
- Jianzhong Cao
Institutions
- Sun Yat-sen University (CN)
- Henan Cancer Hospital (CN)
- Sun Yat-sen University Cancer Center (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-09
- DOI
- https://doi.org/10.3389/fimmu.2025.1729542
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00