Broad immunogenicity of house dust mite proteins contrasts restricted specific IgE and IgG4 associated with allergy
HDM proteins are highly immunogenic and give rise to complex patterns of immune recognition also in the absence of allergy. This has potential implications for the pathogenesis of HDM allergy and the mode of action of allergy immunotherapy.
Authors
- Lars Harder Christensen (ORCID: https://orcid.org/0000-0003-4230-7820)
- Thomas Stranzl (ORCID: https://orcid.org/0000-0003-2221-2736)
- Peter S. Andersen (ORCID: https://orcid.org/0000-0001-7615-8224)
- Jens E. V. Petersen (ORCID: https://orcid.org/0000-0001-5567-465X)
- Jens‐Christian Holm (ORCID: https://orcid.org/0000-0003-4653-342X)
- Peter Adler Würtzen (ORCID: https://orcid.org/0000-0003-1551-2415)
- G. Lund (ORCID: https://orcid.org/0000-0003-2221-7465)
- Niels Johansen (ORCID: https://orcid.org/0000-0002-8947-4688)
- Jakob Wiborg
- Henrik Ipsen
Institutions
- ALK-Abelló (Denmark) (DK)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-02-09
- DOI
- https://doi.org/10.1371/journal.pone.0338593
- Primary Topic
- Allergic Rhinitis and Sensitization
- Type
- article
- Field-Weighted Citation Impact
- 0.00