Abnormal hippocampo-cortical theta-gamma phase-amplitude coupling in Alzheimer’s disease

These findings demonstrate altered hippocampo-cortical temporal coordination in AD and suggest PAC as a potential electrophysiological marker of disease-related network dysfunction.

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Publication Details

Journal
medRxiv
Published
2026-02-09
DOI
https://doi.org/10.64898/2026.02.06.26345635
Primary Topic
Functional Brain Connectivity Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Abnormal hippocampo-cortical theta-gamma phase-amplitude coupling in Alzheimer’s disease

Kamalini G. Ranasinghe, Stefan Haufe, Erfan Baradarantohidi, Srikantan Nagarajan
medRxiv
Functional Brain Connectivity Studies
article

Abnormal hippocampo-cortical theta-gamma phase-amplitude coupling in Alzheimer’s disease

Kamalini G. Ranasinghe, Stefan Haufe, Erfan Baradarantohidi, Srikantan Nagarajan
article en

Abstract

These findings demonstrate altered hippocampo-cortical temporal coordination in AD and suggest PAC as a potential electrophysiological marker of disease-related network dysfunction.

medRxiv
Physikalisch-Technische Bundesanstalt (DE), University of California, San Francisco (US), University of California System (US), University Memory and Aging Center (US), Bernstein Center for Computational Neuroscience Berlin (DE), Technische Universität Berlin (DE), Charité - Universitätsmedizin Berlin (DE)
European Commission, National Institutes of Health
Openalex Percentile: Top 62%
Functional Brain Connectivity Studies
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Abnormal hippocampo-cortical theta-gamma phase-amplitude coupling in Alzheimer’s disease — Kamalini G. Ranasinghe, Stefan Haufe, et al. · medRxiv (2026) | TGRS Research Map | TGRS