Environmental bisphenols hijack the Hmox1 and Cdh1 to trigger premature ovarian insufficiency: A multi-omics investigation
Hmox1 and Cdh1 are pivotal biomarkers for bisphenol-induced POI, modulating apoptosis and endocrine resistance. These targets offer novel therapeutic avenues for environmental toxin-related ovarian dysfunction.
Authors
- Weiyan Tu
- Yuqing Shi
- Haibing Li (ORCID: https://orcid.org/0000-0001-5083-8133)
- Fangfang Xu
- Shaohua Xu
Institutions
- Shanghai First Maternity and Infant Hospital (CN)
Publication Details
- Journal
- Ecotoxicology and Environmental Safety
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.ecoenv.2026.119789
- Primary Topic
- Effects and risks of endocrine disrupting chemicals
- Type
- article
- Field-Weighted Citation Impact
- 0.00