The impact of the Lancet Commission definition of obesity on its prevalence and implications on long-term cardiovascular-kidney-metabolic outcomes in East Asians: Observational study of two community-based cohorts
Adoption of the Lancet Commission definition would classify a small proportion of individuals with BMI of ≥25.0 kg/m2 as non-obese. People with clinical obesity identified by the revised criteria had the highest risks of cardiovascular-kidney-metabolic outcomes including all-cause mortality, whereas individuals reclassified as non-obese had intermediate risks of cardiovascular-kidney-metabolic outcomes between those in pre-clinical obesity and overweight categories.
Authors
- CHI HO LEE
- Xiaolin Zou (ORCID: https://orcid.org/0009-0003-2254-4703)
- YU CHO WOO
- Tai Hing Lam
- Woo J
- K. S. L. Lam
- Bmy Cheung
- David T. W. Lui
- Kathryn C. B. Tan
- Carol H. Y. Fong
- Hung Fat Tse
- Aimin Xu
- Edward Janus
Institutions
- Department of Health (CN)
- Chinese University of Hong Kong (HK)
- Western Health (AU)
- Pharmaceutical Biotechnology (Czechia) (CZ)
- University of Hong Kong (HK)
Publication Details
- Journal
- PLoS Medicine
- Published
- 2026-02-09
- DOI
- https://doi.org/10.1371/journal.pmed.1004749
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.00