The impact of the Lancet Commission definition of obesity on its prevalence and implications on long-term cardiovascular-kidney-metabolic outcomes in East Asians: Observational study of two community-based cohorts

Adoption of the Lancet Commission definition would classify a small proportion of individuals with BMI of ≥25.0 kg/m2 as non-obese. People with clinical obesity identified by the revised criteria had the highest risks of cardiovascular-kidney-metabolic outcomes including all-cause mortality, whereas individuals reclassified as non-obese had intermediate risks of cardiovascular-kidney-metabolic outcomes between those in pre-clinical obesity and overweight categories.

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Journal
PLoS Medicine
Published
2026-02-09
DOI
https://doi.org/10.1371/journal.pmed.1004749
Primary Topic
Chronic Kidney Disease and Diabetes
Type
article
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article

The impact of the Lancet Commission definition of obesity on its prevalence and implications on long-term cardiovascular-kidney-metabolic outcomes in East Asians: Observational study of two community-based cohorts

CHI HO LEE, Xiaolin Zou, YU CHO WOO, Tai Hing Lam et al.
PLoS Medicine
Chronic Kidney Disease and Diabetes
article

The impact of the Lancet Commission definition of obesity on its prevalence and implications on long-term cardiovascular-kidney-metabolic outcomes in East Asians: Observational study of two community-based cohorts

CHI HO LEE, Xiaolin Zou, YU CHO WOO, Tai Hing Lam, Woo J, K. S. L. Lam, Bmy Cheung, David T. W. Lui, Kathryn C. B. Tan, Carol H. Y. Fong, Hung Fat Tse, Aimin Xu, Edward Janus
article en

Abstract

Adoption of the Lancet Commission definition would classify a small proportion of individuals with BMI of ≥25.0 kg/m2 as non-obese. People with clinical obesity identified by the revised criteria had the highest risks of cardiovascular-kidney-metabolic outcomes including all-cause mortality, whereas individuals reclassified as non-obese had intermediate risks of cardiovascular-kidney-metabolic outcomes between those in pre-clinical obesity and overweight categories.

PLoS MedicineVol. 23(2)
Department of Health (CN), Chinese University of Hong Kong (HK), Western Health (AU), Pharmaceutical Biotechnology (Czechia) (CZ), University of Hong Kong (HK)
Good health and well-being
Openalex Percentile: Top 66%
Chronic Kidney Disease and Diabetes
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The impact of the Lancet Commission definition of obesity on its prevalence and implications on long-term cardiovascular-kidney-metabolic outcomes in East Asians: Observational study of two community-based cohorts — CHI HO LEE, Xiaolin Zou, et al. · PLoS Medicine (2026) | TGRS Research Map | TGRS