Clinicopathological features and diagnostic challenges of hepatic epithelioid angiomyolipoma: a retrospective analysis of 27 cases

Hepatic epithelioid angiomyolipoma presents with non-specific clinical and radiological features, making preoperative diagnosis challenging and often leading to misdiagnosis as other common liver tumors. Definitive diagnosis depends on histopathological and immunohistochemical analysis. Surgical resection remains the primary treatment due to the tumor's malignant potential. A high index of suspicion and reliance on pathological confirmation are crucial for accurate management of this rare tumor.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-02-09
DOI
https://doi.org/10.3389/fmed.2026.1729519
Primary Topic
Tuberous Sclerosis Complex Research
Type
article
Field-Weighted Citation Impact
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article

Clinicopathological features and diagnostic challenges of hepatic epithelioid angiomyolipoma: a retrospective analysis of 27 cases

Yizhuo Shi, Hongzhen Wei, E Cai, Shiran Sun et al.
Frontiers in Medicine
Tuberous Sclerosis Complex Research
article

Clinicopathological features and diagnostic challenges of hepatic epithelioid angiomyolipoma: a retrospective analysis of 27 cases

Yizhuo Shi, Hongzhen Wei, E Cai, Shiran Sun, Chidan Wan
article en

Abstract

Hepatic epithelioid angiomyolipoma presents with non-specific clinical and radiological features, making preoperative diagnosis challenging and often leading to misdiagnosis as other common liver tumors. Definitive diagnosis depends on histopathological and immunohistochemical analysis. Surgical resection remains the primary treatment due to the tumor's malignant potential. A high index of suspicion and reliance on pathological confirmation are crucial for accurate management of this rare tumor.

Frontiers in MedicineVol. 13
Huazhong University of Science and Technology (CN)
Openalex Percentile: Top 60%
Tuberous Sclerosis Complex Research
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