Feasibility and Outcomes of Perirectal Spacer Implantation in Previously Treated Prostate Cancer Patients Undergoing Salvage Proton Therapy Radiation

This is the first reported study evaluating the feasibility of perirectal spacer implantation in men with prior treatment to the pelvis, undergoing salvage radiation with protons. Our report shows perirectal spacer implantation is feasible and safe in patients undergoing salvage proton therapy, including those with prior EBRT or BT. Although technically more challenging in HIFU-treated patients, successful placement was achieved in the majority, with minimal toxicity and favorable dosimetric outcomes, although longer follow-up is needed.