Pharmacist-led multidisciplinary review of carbapenem use in inpatients: A quasi-experimental study

The clinical pharmacist-led MDT model enhances carbapenem-prescribing appropriateness and fosters interprofessional collaboration. Its implementation was associated with shorter hospital stays and improvements in key clinical indicators, including reduced ICU admission and mortality. However, the observed shifts in resistant pathogen epidemiology underscore that antimicrobial stewardship strategies must be integrated with rigorous infection prevention and control measures to simultaneously optimise therapeutic outcomes and mitigate resistance.

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Publication Details

Journal
Journal of Global Antimicrobial Resistance
Published
2026-02-09
DOI
https://doi.org/10.1016/j.jgar.2026.02.001
Primary Topic
Antibiotic Use and Resistance
Type
article
Field-Weighted Citation Impact
0.00
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article

Pharmacist-led multidisciplinary review of carbapenem use in inpatients: A quasi-experimental study

Tingting Nan, Xianni Wei, Yumei Cai, Siheng Lian et al.
Journal of Global Antimicrobial Resistance
Antibiotic Use and Resistance
article

Pharmacist-led multidisciplinary review of carbapenem use in inpatients: A quasi-experimental study

Tingting Nan, Xianni Wei, Yumei Cai, Siheng Lian, Jinbao Wei, Xiaoyun Ye, Yonglong Su
article en

Abstract

The clinical pharmacist-led MDT model enhances carbapenem-prescribing appropriateness and fosters interprofessional collaboration. Its implementation was associated with shorter hospital stays and improvements in key clinical indicators, including reduced ICU admission and mortality. However, the observed shifts in resistant pathogen epidemiology underscore that antimicrobial stewardship strategies must be integrated with rigorous infection prevention and control measures to simultaneously optimise therapeutic outcomes and mitigate resistance.

Journal of Global Antimicrobial ResistanceVol. 47
Xiamen Chang Gung Hospital (CN), Xiamen Medical College
Good health and well-being
Openalex Percentile: Top 55%
Antibiotic Use and Resistance
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