Analgesic efficacy of oral tramadol–dipyrone combination in cats undergoing ovariohysterectomy

The combination of dipyrone and tramadol in a single oral formulation provided superior analgesia and fewer adverse effects than either drug alone. Cats in the combination group required less rescue medication, had significantly lower cortisol values, and experienced fewer side effects.

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Publication Details

Journal
Frontiers in Veterinary Science
Published
2026-02-09
DOI
https://doi.org/10.3389/fvets.2026.1773463
Primary Topic
Veterinary Pharmacology and Anesthesia
Type
article
Field-Weighted Citation Impact
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article

Analgesic efficacy of oral tramadol–dipyrone combination in cats undergoing ovariohysterectomy

Aline Magalhães Ambrósio, Jéssica Sperandio Cavaco, Júlia Maria Matera, Isabela Torquato de Lima et al.
Frontiers in Veterinary Science
Veterinary Pharmacology and Anesthesia
article

Analgesic efficacy of oral tramadol–dipyrone combination in cats undergoing ovariohysterectomy

Aline Magalhães Ambrósio, Jéssica Sperandio Cavaco, Júlia Maria Matera, Isabela Torquato de Lima, Marco Aurélio Amador Pereira, Karina Velloso Braga Yazbek, Amanda Cologneze Brito, Denise Tabacchi Fantoni, Érica Vilela Barreto
article en

Abstract

The combination of dipyrone and tramadol in a single oral formulation provided superior analgesia and fewer adverse effects than either drug alone. Cats in the combination group required less rescue medication, had significantly lower cortisol values, and experienced fewer side effects.

Frontiers in Veterinary ScienceVol. 13
Universidade de São Paulo (BR), Biolab Pharma (Brazil) (BR)
Openalex Percentile: Top 61%
Veterinary Pharmacology and Anesthesia
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Analgesic efficacy of oral tramadol–dipyrone combination in cats undergoing ovariohysterectomy — Aline Magalhães Ambrósio, Jéssica Sperandio Cavaco, et al. · Frontiers in Veterinary Science (2026) | TGRS Research Map | TGRS