Synthetic peptide V11A reduces bacterial load and inflammation in pneumococcal meningitis
Our results support the potential of therapeutic peptide to reduce the bacterial burden and mitigate the inflammatory response in pneumococcal meningitis.
Authors
- Lucy J. Hathaway (ORCID: https://orcid.org/0000-0002-5361-5397)
- Stephen L. Leib (ORCID: https://orcid.org/0000-0002-1106-6123)
- Denis Grandgirard (ORCID: https://orcid.org/0000-0002-4151-5196)
- Hannah N. Agnew (ORCID: https://orcid.org/0000-0002-7640-4015)
- Janine Lux
- Roger Koller (ORCID: https://orcid.org/0000-0002-8502-9704)
- Maria Erhardt
- Robert Hoepner
- Linus Rechsteiner
Institutions
- University of Bern (CH)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2026-02-09
- DOI
- https://doi.org/10.3389/fcimb.2025.1686525
- Primary Topic
- Antimicrobial Peptides and Activities
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science Foundation
- University of Bern
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung