In vivo evaluation of a biodegradable intraanastomotic membrane in a porcine model
This proof-of-concept study demonstrates that the PDO membrane can be safely incorporated into stapled anastomoses without compromising anastomotic healing. The membrane provides a stable, biocompatible platform suitable for future sensor integration, supporting the development of a diagnostic intraanastomotic device.
Authors
- Julia Henne
- Friedrich Prall (ORCID: https://orcid.org/0000-0001-8103-5544)
- Richard Kantelberg (ORCID: https://orcid.org/0000-0002-3959-2889)
- Amelie Zitzmann (ORCID: https://orcid.org/0000-0003-4318-4017)
- Finn Jaekel (ORCID: https://orcid.org/0000-0001-9115-968X)
- Hans Kleemann (ORCID: https://orcid.org/0000-0002-9773-6676)
- Brigitte Vollmar (ORCID: https://orcid.org/0000-0002-2403-9597)
- Daniel C. Freund (ORCID: https://orcid.org/0009-0005-6950-5343)
- Jochen Hampe
- Dennis Wahl
- Karl Leo
- Clemens Schafmayer
- Sebastian Hinz
Institutions
- University Medical Center (US)
- Universitätsmedizin Göttingen (DE)
- University of Rostock (DE)
- University of Göttingen (DE)
- Technische Universität Dresden (DE)
Publication Details
- Journal
- Frontiers in Surgery
- Published
- 2026-02-09
- DOI
- https://doi.org/10.3389/fsurg.2026.1746520
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft
- European Regional Development Fund