Therapeutic Efficacy of Risankizumab for Small-Intestinal Lesions in Crohn’s Disease: A Retrospective Study Using Double-Balloon Endoscopy

This study confirms the therapeutic efficacy of RZB for deep small-intestinal involvement in CD based on comprehensive DBE assessment. The results support the clinical utility of RZB in patients with refractory small-intestinal lesions, highlighting its potential to maintain 1 year disease control when ongoing mucosal inflammation is a concern. These findings underscore the importance of deep enteroscopic evaluation to optimize therapeutic strategies.

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Publication Details

Journal
Digestion
Published
2026-02-09
DOI
https://doi.org/10.1159/000550396
Primary Topic
Inflammatory Bowel Disease
Type
article
Field-Weighted Citation Impact
0.00
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article

Therapeutic Efficacy of Risankizumab for Small-Intestinal Lesions in Crohn’s Disease: A Retrospective Study Using Double-Balloon Endoscopy

Takashi Hirose, Tsunaki Sawada, Kentaro Murate, Kazuhiro Furukawa et al.
Digestion
Inflammatory Bowel Disease
article

Therapeutic Efficacy of Risankizumab for Small-Intestinal Lesions in Crohn’s Disease: A Retrospective Study Using Double-Balloon Endoscopy

Takashi Hirose, Tsunaki Sawada, Kentaro Murate, Kazuhiro Furukawa, Yasuyuki Mizutani, Kentaro YAMAO, Takeshi Yamamura, Masanao Nakamura, Tadashi Iida, Yoji Ishizu, Eri Ishikawa, Hiroki Kawashima, Takuya Ishikawa, Takashi Honda, Keiko Maeda
article en

Abstract

This study confirms the therapeutic efficacy of RZB for deep small-intestinal involvement in CD based on comprehensive DBE assessment. The results support the clinical utility of RZB in patients with refractory small-intestinal lesions, highlighting its potential to maintain 1 year disease control when ongoing mucosal inflammation is a concern. These findings underscore the importance of deep enteroscopic evaluation to optimize therapeutic strategies.

Digestion
Nagoya University Hospital (JP), Nagoya University (JP)
Good health and well-being
Openalex Percentile: Top 59%
Inflammatory Bowel Disease
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Therapeutic Efficacy of Risankizumab for Small-Intestinal Lesions in Crohn’s Disease: A Retrospective Study Using Double-Balloon Endoscopy — Takashi Hirose, Tsunaki Sawada, et al. · Digestion (2026) | TGRS Research Map | TGRS