Preclinical evaluation of Senna alata leaf extract against Hymenolepis diminuta: a promising natural anthelmintic solution

This study demonstrates the potent antiparasitic effects of S. alata against H. diminuta in a rodent model. The alcoholic leaf extract of S. alata, particularly at 1000 mg/kg, exhibits strong antiparasitic efficacy against H. diminuta, alongside notable improvements in host hematological and organ function parameters. Its non-toxic nature reinforces its potential as a safe, natural anthelmintic, warranting further exploration for therapeutic applications.

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Publication Details

Journal
BMC Complementary Medicine and Therapies
Published
2026-02-09
DOI
https://doi.org/10.1186/s12906-025-05230-0
Primary Topic
Helminth infection and control
Type
article
Field-Weighted Citation Impact
0.00
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article

Preclinical evaluation of Senna alata leaf extract against Hymenolepis diminuta: a promising natural anthelmintic solution

Saptarshi Roy, Larisha M. Lyndem
BMC Complementary Medicine and Therapies
Helminth infection and control
article

Preclinical evaluation of Senna alata leaf extract against Hymenolepis diminuta: a promising natural anthelmintic solution

Saptarshi Roy, Larisha M. Lyndem
article en

Abstract

This study demonstrates the potent antiparasitic effects of S. alata against H. diminuta in a rodent model. The alcoholic leaf extract of S. alata, particularly at 1000 mg/kg, exhibits strong antiparasitic efficacy against H. diminuta, alongside notable improvements in host hematological and organ function parameters. Its non-toxic nature reinforces its potential as a safe, natural anthelmintic, warranting further exploration for therapeutic applications.

BMC Complementary Medicine and TherapiesVol. 26(1)
Visva-Bharati University (IN)
Openalex Percentile: Top 61%
Helminth infection and control
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