Hobnail hemangioma–a systematic review and a case report of an intraoral lesion with Dabska tumor-like features

Hobnail hemangioma is a rare, benign vascular neoplasm. Intraoral lesions are extremely rare. To date, only seven intraoral cases of hobnail hemangiomas and two intraoral cases of Dabska tumors have been described in the English-language literature. This article presents a hobnail hemangioma case with papillary intralymphatic angioendothelioma (Dabska tumor)-like features on the gingiva of a 7-year-old female. Hobnail hemangiomas are benign lesions, but they display worrisome features on microscopic examination and can be confused with malignant vascular neoplasms. Histologically hobnail hemangiomas demonstrate superficial dilated, vascular structures with prominent hobnail endothelial cells and deeper, collagen dissecting thinner neoplastic vessels which in some cases may raise a worrisome pseudoangiosarcomatous histologic view. It is important to set an accurate diagnosis of hobnail hemangioma to diminish the risk of diagnosing these lesions as malignant tumors thus avoiding unnecessarily aggressive therapy.

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Publication Details

Journal
Diagnostic Pathology
Published
2026-02-09
DOI
https://doi.org/10.1186/s13000-026-01750-6
Primary Topic
Vascular Malformations and Hemangiomas
Type
article
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article

Hobnail hemangioma–a systematic review and a case report of an intraoral lesion with Dabska tumor-like features

Jetta Kelppe, Tommy Wilkman, Tuula Anneli Salo, Jouko Lohi et al.
Diagnostic Pathology
Vascular Malformations and Hemangiomas
article

Hobnail hemangioma–a systematic review and a case report of an intraoral lesion with Dabska tumor-like features

Jetta Kelppe, Tommy Wilkman, Tuula Anneli Salo, Jouko Lohi, Riitta Hannele Pajukanta, Elina Mari Susanna Salasuo, Hellevi Merja Anneli Ruokonen
article en

Abstract

Hobnail hemangioma is a rare, benign vascular neoplasm. Intraoral lesions are extremely rare. To date, only seven intraoral cases of hobnail hemangiomas and two intraoral cases of Dabska tumors have been described in the English-language literature. This article presents a hobnail hemangioma case with papillary intralymphatic angioendothelioma (Dabska tumor)-like features on the gingiva of a 7-year-old female. Hobnail hemangiomas are benign lesions, but they display worrisome features on microscopic examination and can be confused with malignant vascular neoplasms. Histologically hobnail hemangiomas demonstrate superficial dilated, vascular structures with prominent hobnail endothelial cells and deeper, collagen dissecting thinner neoplastic vessels which in some cases may raise a worrisome pseudoangiosarcomatous histologic view. It is important to set an accurate diagnosis of hobnail hemangioma to diminish the risk of diagnosing these lesions as malignant tumors thus avoiding unnecessarily aggressive therapy.

Diagnostic PathologyVol. 21(1)
University of Helsinki (FI), Oulu University Hospital (FI), Helsinki University Hospital (FI), National Medical Research Center of Dentistry and Maxillofacial Surgery (RU), University of Oulu (FI)
Openalex Percentile: Top 62%
Vascular Malformations and Hemangiomas
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