Outcomes of Unicompartmental Knee Arthroplasty in Patients Receiving Glucagon-like Peptide 1 Agonist Therapy: A Matched Cohort Study

Our study showed that patients receiving GLP-1 agonists did not have increased rates of adverse surgical outcomes following UKA; however, we could not definitively conclude that GLP-1 agonists served as a protective factor for decreasing complications. Given the expanding usage of GLP-1 agonists, prospective research is needed to delineate these potential risks or benefits.

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Publication Details

Journal
Arthroplasty Today
Published
2026-02-09
DOI
https://doi.org/10.1016/j.artd.2026.101958
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Outcomes of Unicompartmental Knee Arthroplasty in Patients Receiving Glucagon-like Peptide 1 Agonist Therapy: A Matched Cohort Study

Bailey J. Ross, Kevin Heo, Jerry C. Chang, Jacob A Worden et al.
Arthroplasty Today
Diabetes Treatment and Management
article

Outcomes of Unicompartmental Knee Arthroplasty in Patients Receiving Glucagon-like Peptide 1 Agonist Therapy: A Matched Cohort Study

Bailey J. Ross, Kevin Heo, Jerry C. Chang, Jacob A Worden, Emilio Arellano, Jacob M. Wilson, Anthony L. Karzon, Ajay Premkumar
article en

Abstract

Our study showed that patients receiving GLP-1 agonists did not have increased rates of adverse surgical outcomes following UKA; however, we could not definitively conclude that GLP-1 agonists served as a protective factor for decreasing complications. Given the expanding usage of GLP-1 agonists, prospective research is needed to delineate these potential risks or benefits.

Arthroplasty TodayVol. 38
Emory University (US), Augusta University (US)
Good health and well-being
Openalex Percentile: Top 64%
Diabetes Treatment and Management
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